Dynamic contact network between ribosomal subunits enables rapid large-scale rotation during spontaneous translocation
نویسندگان
چکیده
منابع مشابه
Dynamic contact network between ribosomal subunits enables rapid large-scale rotation during spontaneous translocation
During ribosomal translation, the two ribosomal subunits remain associated through intersubunit bridges, despite rapid large-scale intersubunit rotation. The absence of large barriers hindering rotation is a prerequisite for rapid rotation. Here, we investigate how such a flat free-energy landscape is achieved, in particular considering the large shifts the bridges undergo at the periphery. The...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 2015
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/gkv649